HOPA Oral Chemotherapy Collaborative (OCC)™️

Oncology patient talking to a medical proffesional


The HOPA Oral Chemotherapy Collaborative (OCC) is a member-created program that seeks to optimize the care of individuals who take oral anticancer agents (OAAs) for the treatment of their cancer. There are four main ways in which we do this:

  1. Incorporating the quality and value of oncology pharmacists in the management of OAAs, particularly within HOPA’s current and future strategic initiatives
  2. Identifying and developing opportunities for the HOPA membership to participate in education, training, and research focused on OAA best practices
  3. Identifying, providing guidance, and promoting OAA best practices within HOPA’s 4 pillars (Education, Advocacy, Research, and Professional Practice)
  4. Fostering and prioritizing collaborative relationships with external organizations to promote best practices or Oral Chemotherapy including education, research, and advocacy

Oral Chemotherapy Resources

The growing number of oral medications for the treatment of cancer over the past decade has revolutionized oncology care, providing many new options for cancer treatment. HOPA recognizes these new options also create common practice challenges. The following are practice tools, standards, and guidelines that HOPA recommends for use in the management of oral chemotherapy.

Patient Education

Click on organization links below, to have access to their patient-focused information.
Oral Chemotherapy Education (OCE)
Oncology Nursing Society (ONS)
Association of Community Care Centers (ACCC)
Hematology Oncology Pharmacy Association (HOPA)

Guidelines/Best Practices

2016 Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology

NCCN Task Force Report: Oral Chemotherapy

QOPI Oral Chemotherapy Measures and Relevant General Chemotherapy Measures

General Resources

HOPA Website Resources

MOQC Oral Resources

ONS Oral Therapy Resources

Therapy Initiation

Initiation Checklist Initiation Checklist for a New Start Oral Chemotherapy

Prescribing Recommendations

FDA Drugs Site

Medication Reconciliation

AHRQ Medications at Transitions and Clinical Handoffs (MATCH) Toolkit for Medication Reconciliation

Joint Commission 2017 National Patient Safety Goals (NPSG.03.06.01)

Drug-Drug, Drug-Herb, and Drug-Food Interaction Resources

Indiana University Drug Interaction Site

Drug-Drug Interactions With Oral Antineoplastic Agents (2017)

Oral Chemotherapy Food and Drug Interactions: A Comprehensive Review of the Literature (2013)

Recommendations for Taking Oral Antineoplastics with Regard to Food

Memorial Sloan Kettering Cancer Center Integrative Medicine Site (Herbs)

Financial Resources

ASCO Managing the Cost of Cancer Care

NCCN Virtual Reimbursement Resource Room

Michigan Society of Hematology and Oncology MSHO Patient Support Resources


Multinational Association for Supportive Care in Cancer (MASCC) Oral Agent Teaching Tool (MOATT)

Oncolink Education Resources

Chemocare Managing Side Effects

ONS Oral Chemo Guide

MOQC Drug Specific Resources

Safe-Handling/Disposal/Other General

Safe Handling of Oral Chemotherapeutic Agents in Clinical Practice: Recommendations From an International Pharmacy Panel (2010)

Reproductive/Fertility Resources

Fertility Preservation for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update


Patient Reported Outcomes (PRO) Tools

Edmonton Symptom Assessment Scale

Implementing a Method for Evaluating Patient-Reported Outcomes Associated With Oral Oncolytic Therapy (2017)

Utilizing Patient Reported Outcomes for Patients Receiving Oral Chemotherapy (2017)

MD Anderson Symptom Inventory

Overall survival results of a randomized trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment (2017)


MASCC Symptom Management

ASCO Antiemetic Guidelines (2017)


Adherence Overview (2016)

Review of the four item Morisky Medication Adherence Scale (MMAS-4) and eight item Morisky Medication Adherence Scale (MMAS-8) (2014)

The relationship between patient activation, confidence to self-manage side effects, and adherence to oral oncolytics: a pilot study with Michigan oncology practices (2017)

Nonadherence to Imatinib Treatment in Patients with Gastrointestinal Stromal Tumors: The ADAGIO Study (2011)

Mobile Application to Promote Adherence to Oral Chemo and Symptom Management (2017)

Monitoring Parameters

FDA Drugs Site

NCCN Chemotherapy Order Templates

Avella Oral Oncology Monitoring and Counseling