HOPA Oral Chemotherapy Collaborative (OCC)®
About the OCC
The HOPA Oral Chemotherapy Collaborative (OCC) is a volunteer group that seeks to optimize the care of individuals who take oral anticancer agents (OAAs) for the treatment of their cancer. There are four main ways in which we do this:
- Incorporating the quality and value of oncology pharmacists in the management of OAAs, particularly within HOPA’s current and future strategic initiatives
- Identifying and developing opportunities for the HOPA membership to participate in education, training, and research focused on OAA best practices
- Identifying, providing guidance, and promoting OAA best practices within HOPA’s 4 pillars (Education, Advocacy, Research, and Professional Practice)
- Fostering and prioritizing collaborative relationships with external organizations to promote best practices or Oral Chemotherapy including education, research, and advocacy
Oral Chemotherapy Resources
The growing number of oral medications for the treatment of cancer over the past decade has revolutionized oncology care, providing many new options for cancer treatment. HOPA recognizes these new options also create common practice challenges. The following are practice tools, standards, and guidelines that HOPA recommends for use in the management of oral chemotherapy.
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Patient Education
This section includes resources that provide education related to oral oncolytic therapies, including general information and medication specific resources.
Guidelines/Best Practices
This section includes best practices and guidelines to support safe, high-quality, patient-centered use of oral oncolytic therapies.
- 2018 HOPA Best Practices for the Management of Oral Oncolytic Therapy: Pharmacy Practice Standard
- Antineoplastic Therapy Adminstration Safety Standards for Adult and Pediatric Oncology: ASCO-ONS Standards
- ASHP Guidelines on Preventing Medication Errors with Chemotherapy and Biotherapy
- American Society of Clinical Oncology-Quality Oncology Practice Initiative (ASCO-QOPI): This sub-section contains links to QOPI general program information, program quality metrics, and publication detailing experience seeking QOPI certification
Drug-Drug, Drug-Herb, and Drug-Food Interaction Resources
This section includes resources on various drug interactions - including drug-drug, drug-herb, and drug-food interactions.
- Indiana University Drug Interaction Site
- Managing Drug Interactions with Oral Anticancer Treatments
- Evidence- and Consensus-Based Guidelines for Drug-Drug Interactions with Anticancer Drugs: A Practical and Universal Tool for Management
- About Herbs - Memorial Sloan Kettering Cancer Center Integrative Medicine Site
- CANNabinoid Drug Interaction Review (CANN-DIR®) - Penn State
- Clinical Relevance of Drug Interactions with Cannabis: A Systematic Review
- Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guidelines
- Opportunities for Pharmacogenomics-Guided Supportive Care in Cancer
- Cancer Therapy Interactions with Foods and Dietary Supplements (National Cancer Institute PDQ®)
Financial Resources
This section includes financial resources that may help patients make their oral oncolytic care more affordable. It includes links to drug manufacturer patient programs, grants for various cancer types, and more.
Safe-Handling/Disposal
This section includes resources and links to information and guidelines on how to safely handle and dispose of cancer care drugs - both in practice and home settings.
Monitoring
This section contains links to symptom monitoring resources.
- NCCN Chemotherapy Order Templates (note: This resource requires a paid subscription)
- Implementing a Method for Evaluating Patient-Reported Outcomes Associated with Oral Oncolytic Therapy (2017)
- Utilizing Patient Reported Outcomes for Patients Receiving Oral Chemotherapy (2017)
- MD Anderson Symptom Inventory
- Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment
- Routine Surveillance of Chemotherapy Toxicities in Cancer Patients Using the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)
Symptoms
These resources provide guidance in assessing and managing common toxicities related to oral anticancer agents.
Adherence
Resources in this section include landmark trials concerning adherence to oral anticancer agents.
