BCOP Updates 2025: Updates in Carcinoma of Unknown Primary
Carcinomas of unknown primary are uncommon but can pose treatment challenges for providers and confer a poor prognosis for the patients. Chemotherapy options are limited and typically chosen based on pathological findings. Molecular profiling and use of next-generation sequencing can help guide therapy in some cases. This update will review current treatment recommendations.
BCOP Updates 2025: Updates in Carcinoma of Unknown Primary
Author: Isabel Houlzet, PharmD, BCOP
Learning Objectives
- Review carcinoma of unknown primary (CUP) and recommended systemic treatment options based on tumor histology
- Describe the role of molecular profiling in CUP and its potential impact in care
- Interpret recent clinical trial data for tumor-agonistic indications in treating patients with select tumor markers
- Demonstrate the importance of multidisciplinary and individualized care for this patient population
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Knowledge Course for Pharmacists
Technology requirements: HOPA Learn requires a modern web browser (Internet Explorer 7+, Mozilla Firefox, Apple Safari, Google Chrome) and the ability to listen to audio with the content.

HOPA is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. In order to claim BCOP credit, you must pass the BCOP Post-Test with a 75% or higher.
All CE hours will be transmitted to the CPE Monitor and BPS within 1-2 weeks of course completion.