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Preconference Session
Wednesday, March 21, 20127:15-11:45 am
Oncology Boot Camp
(This session is a separate $50 registration fee) (.425 CEUs) Until very recently, schools of pharmacy have not incorporated the background cellular biology of cancer necessary to understand the new biologically target therapies, their mechanisms of actions, and their drug-drug and drug-disease state interactions. This knowledge-based activity will provide the biologic background necessary to understand these concepts, pharmacologic agents, and the pharmacist’s role in the management of these unique agents.
Boot Camp Goals
- To provide a formal introduction and overview of pharmacological agents considered to be "nontraditional chemotherapeutics" for hematology/oncology pharmacy trainees, pharmacy practitioners new to the field of hematology/oncology (i.e., <3–5 years of professional experience and pharmacists not solely practicing in hematology/oncology regardless of their years of experience.
- To develop and foster professional relationships with pharmacists working and residing in the city and surrounding area where the annual conference is being held.
- To become a leading and primary source for the next generation of hematology/oncology pharmacists requiring professional education.
Schedule
7:15-7:30 am
Welcome and Introductions
7:30-8:45 am
Cell Cycle Control, Angiogenesis, and Mitogenic Signaling Cascade: Things That Help Cancer Grow. Things That Pharmacists Need to Know
Patrick Medina, PharmD BCIO
Learning Objectives
- Describe normal angiogenesis and compare and contrast normal vasculature from neoplasm derived vasculature.
- Describe select intracellular signaling pathways and their relationships to one another.
- List disruptions in the intracellular signaling cascade that contribute to the neoplastic phenotype.
- Identify therapeutic targets within select intracellular signaling pathways.
8:45-9:35 am
Tyrosine Kinase Inhibitors in Hematology (Focus on the Philadelphia Chromosome)
Chris Fausel, PharmD
Learning Objectives
- List tyrosine kinase inhibitors used in chronic myeloid leukemia treatment.
- Compare and contrast agents used for these treatments.
- Discuss the utility of these agents in acute lymphoblastic leukemia (pediatric or adult).
9:35-9:45 am
Refreshment Break
9:45-10:35 am
Tour of Tyrosine Kinase Inhibitors in Oncology
Andrea Iannucci, PharmD BCOP
Learning Objectives
- Describe evolution of receptor tyrosine kinase inhibitors (TKIs) in lung cancer.
- Understand the use of multitarget TKIs in renal cell cancer.
- Describe the rationale for using TKIs in solid tumor malignancies
10:35-10:40 am
Break
10:40-11:40 am
Getting a TKO on TKI Toxicities
Lydia Mis, PharmD BCOP
Learning Objectives
- Compare and contrast common toxicities of tyrosine kinase inhibitors (TKIs) and their mechanisms.
- Describe why traditional grading systems may not be appropriate for the management of TKI-related toxicities.
- Identify supportive care management in various TKI toxicities by organ system.
- Evaluate potential drug-drug interactions of TKIs and strategies for dose adjustments.
